• Gjorgji Shumanov University "Goce Delchev"- Stip
  • Gordana Panova University "Goce Delchev"- Stip
  • Marija Koteva University "Goce Delchev"- Stip
Keywords: gallbladder, risk factors, gallstones, incidence, cholecystectomy


Cholelithiasis is the presence of gallstones, that is, concretions formed in the gallbladder. Cholesterol Cholelithiasis is one of the most common digestive diseases in Western countries. At least 20 million Americans (≈12% of adults) have stones in the bile. The prevalence of cholelithiasis is assumed to increase due to obesity, associated with resistance to insulin and metabolic syndrome. Aims: Analysis, elaboration and presentation of the data which presents the epidemiologic state of the cholelithiasis in the East and the Southeast Region of Republic od Macedonia in period of five years (2012-2016). Materials and methods:An epidemiological- descriptive method and retrospective analysis of the patients data have been used for the survey. Overall, 2350 patients data with cholelithiasis from Stip and Strumica and their surrounding places has been elaborated and compared one to another based on the gender ,age, place of living, year of diagnosing and number of the days of hospital stay for treating the cholelithiasis. Results:The total number of patients with cholethiasis in East and Southeast region is 2350, which the majority of patients are been registered in 2016 with 505 cases (21,4%), while the minority of the total number of the patients with gallstones are been registered in 2014 with419 cases (17,8%). According to the gender, women are twice as much affected than men, with 66,8 % of the cases (33,2% men), while the biggest amount of those registered patients are between 55 and 64 years. In the Southeast region, 709 patients underwent cholecystectomy due to gallstones, with culmination in 2015 (70,3%). Most of these patients were females and the most affected age group is between 55 and 64 years. Conclussions:During the analysis period, the incidence of the cholelithiasis increases with age, with peak in the age group between 55 and 64. Significantly is more common in women, affecting them twice as much than men


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How to Cite
Shumanov, G., Panova, G., & Koteva, M. (2017). CHOLELITHIASIS IN EAST AND SOUTHEAST REGION OF REPUBLIC OF MACEDONIA. Knowledge International Journal, 19(4), 1411 - 1416. Retrieved from