TY - JOUR AU - Nikolova, Velice AU - Velickova, Nevenka PY - 2020/06/19 Y2 - 2024/03/29 TI - THE IMPORTANCE OF IMMUNOFLUOROMETRIC METHOD (DELFIA) IN EARLY DIAGNOSTICS AND SCREENING OF CONGENITAL HYPOTHYROIDISM JF - KNOWLEDGE - International Journal JA - kij VL - 40 IS - 4 SE - Articles DO - UR - https://ikm.mk/ojs/index.php/kij/article/view/829 SP - 673 - 679 AB - <p>Congenital hypothyroidism is inadequate thyroid hormone production in newborn infants. It can occur because of an anatomic defect in the gland, an inborn error of thyroid metabolism, or iodine deficiency. This is the most common neonatal endocrine disorder, and historically, thyroid dysgenesis was thought to account for approximately 80% of cases.<br>The aim of this article is to emphasize the importance of the DELFIA method as a common molecular biological methods in early diagnostics and screening of neonatal congenital hypothyroidism and further treatment. The research uses a descriptive approach that includes detail comparation and review of results about congenital hypothyroidism during today, also this article include and evalueted results based on the research from the Public Health Institution Clinical Hospital - Stip, for the period from 2016 to 2018.<br>As a conclusion of this article, based from our results from the Public Health Institution Clinical Hospital - Stip and results from other authors and clinical research in the world, with detail explanation of this immunofluorometric method DELFIA we want to highlights the importance of this method in early laboratory diagnostics and daily routine technics and screening of congenital hypothyroidism and and further treatment.</p> ER -