OSTEOPOROSIS IN MEN - A DIAGNOSTIC CHALLENGE AND SCREENING STRATEGIES IN AT-RISK PATIENTS

Authors

  • Maria Nedkova UMНAT-AD, Burgas, Bulgaria

Keywords:

osteoporosis, risk patients, fracture risk, screening, disability

Abstract

With an aging population, osteoporosis in men is increasing as a public health problem. One seventh of osteoporotic vertebral compression fractures and one quarter of hip fractures are known to result from osteoporosis in men. It is expected by 2050. the incidence of hip fractures worldwide to increase by 310% in men. The underestimation of the problem by medical professionals reflects in delayed diagnosis and treatment. The diagnosis of osteoporosis in men continues to be a challenge for healthcare professionals, given poor patient referral and lack of screening strategies for at-risk patients. The processed data showed that, regardless of age, all patients with associated risk factors had low bone mineral density with a high fracture risk and a high ten-year fracture risk. This is due to the lack of screening strategies in the target groups of patients and is associated with delayed initiation of anti-resorptive or bone-building therapy that improves bone density, bone microarchitecture and prevents disability. In this context, attention is focused on awareness measures and early diagnosis in patients at risk of fracture. With a view to screening, knowledge of the risk factors for low bone density and those for fractures is key, which would prevent severe disability and mortality. Given the availability of effective therapies for prevention and treatment, awareness is critical to the prevention of morbidity and mortality as a consequence of fractures.

Author Biography

Maria Nedkova, UMНAT-AD, Burgas, Bulgaria

Department of Rheumatology

References

Борисова, А.-М., Боянов, М., Коларов, Зл., Попиванов, П., и др. (2013). Препоръки за диагностика, профилактика и лечение на дефицит и недостатъчност на Витамин D (pp. 9-13). София, България: Българско Дружество по Ендокринология.

Икономова, К., & Тончева, A. (2010). Нови насоки в костната биология (p.61). София, България.

Петранова, Цв., Шейтанов, Й., & Шейтанов, И. (2016). Остеопороза (pp. 56-149). София, България: “Непрекъснато усъвършенстване“ ЕООД.

Рашков, Р., Петранова, Цв. , Коларов, Зл., Стоилов, Р., и др. (2016). Практическо ръководство по Ревматология. Допълнение I (pp. 324-346). София, България: Централна медицинска библиотека.

Abrahamsen, B., & van Staa, T., Ariely, R., Olson, M., & Cooper,C. (2009). Excess mortality following hip fracture: a systematic epidemiological review. Osteoporosis Int.: 20(10):1633-50. doi: 10.1007/s00198-009-0920-3.

Bandeira, L., Silva, B.C., & Bilezikian, J.P. (2022). Male osteoporosis. Arch Endocrinol Metab: 11;66(5):739-747. doi: 10.20945/2359-3997000000563.

Björnsdottir, S., Clarke,L.Bart., Mannstadt, M., & Bente, L.L. (2022). Male osteoporosis-what are the causes, diagnostic challenges, and management. Best Pract Rest Clin Rheuatol: 36(3):101766. doi: 10.1016/j.berh.2022.101766.

Haentjens, P., Johnell, O., Kanis, J.A., et al. (2004). Evidence From Data Searches and Life-Table Analyses for Gender-Related Differences in Absolute Risk of Hip Fracture After Colles ' or Spine Fracture: Colles 'Fractures as an Early and Sensitive Marker of Skeletal Fragility in White Men. J Bone Miner Res: 19(12):1933-44. doi: 10.1359/JBMR.040917.

Mäkitie, O., & Zillikens, M.C. (2022). Early-Onset Osteoporosis. Calc Tissue Int: 110(5):546-561. doi: 10.1007/s00223-021-00885-6.

Melton III , LJ., & Kallmes, D.F. (2006). Epidemiology of vertebral fractures:Impications for vertebral augmentation. Acad radiol; 13(5):538-45. doi: 10.1016/j.acra.2006.01.005.

Nevitt, M.C., Ettinger, B., & Black, D.M. (1998). The association of radiologically detected vartabral fractures with back pain and function : a prospective study.Ann Intern Med; 128(10):793-800. doi: 10.7326/0003-4819-128-10-199805150-00001.

O'Neill, T.W., Felsenberg, D., & Varlow, J. (1996). The prevalence of vertebral deformity in european men and women: the European Vertebral Osteoporosis Study.J Bone Miner Res; 11(7):1010-8. doi: 10.1002/jbmr.5650110719.

Sundeep, K., Shreyasee, A., & Eric, O. (2008). Osteoporosis in Men, Endocrine Reviews, 29(4):441-64. doi: 10.1210/er.2008-0002.

Trombetti, A., Herrmann, F., & Hoffmeyer, P. (2002). Survival and potential years of life lost after hip fracture in men and age-matched women. Osteoporosis Int.; 13(9):731-7. doi: 10.1007/s001980200100

Vilaca, T., Eastell, R., & Schini, M. (2022). Osteoporosis in men. Lancet Diabetes Endocrinol: 10(4):273-283. doi: 10.1016/S2213-8587(22)00012-2.

Xing,Y., Liu, J., Ma, H., & Liu, H. (2022). Relationship of Bone Turnover Markers with Serum Uric Acid-to-Creatinine Ratio in Men and Postmenopausal Women with Type 2 Diabetes. Diabetes Metab Syndr Obes: 15:3205-3217. doi: 10.2147/DMSO.S384694.

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Published

2023-03-31

How to Cite

Nedkova, M. (2023). OSTEOPOROSIS IN MEN - A DIAGNOSTIC CHALLENGE AND SCREENING STRATEGIES IN AT-RISK PATIENTS. KNOWLEDGE - International Journal , 57(4), 499–502. Retrieved from https://ikm.mk/ojs/index.php/kij/article/view/6019