IMPACT OF RADIOACTIVE IODINE THERAPY I-131 ON PATIENT HEALTH QUALITY
Keywords:
Iodine-131, Iodine Radioisotopes, Thyroid Neoplasms, Hyperthyroidism, Hormones, Quality of LifeAbstract
The main indications for therapeutic use of I-131 are treatment of hyperthyroidism, radioactive removal of residual thyroid tissue in malignant thyroid cancers that accumulate iodine, and possible adjuvant therapy of extensive malignancies that accumulate iodine. Treatment with radioactive iodine is used for diffuse hyperthyroidism when medications are not effective for a period or when medications fail to control elevated hormone levels in the blood, as well as for drug-related side effects. I-131 therapy is increasingly replacing surgical treatment because it is simple, economical, practical, and usually has no complications. The aim of this study is to investigate the quality of health of the target group before and after thyroid therapy with radioactive iodine. The study is a prospective study that is conducted from November 2019 to November 2020 in the Clinic for Nuclear Medicine and Endocrinology of the Clinical Center of the of Sarajevo (KCUS) from November 2019 to November 2020. The study including 30 patients who have been injected with I-131 for the treatment of thyroid disease and undergo regular check-ups and examinations at the Nuclear Medicine and Endocrinology Clinic of KCUS. The results show that patients felt better after treatment with radioactive iodine, which is confirmed by the Wilcoxon test for paired samples (p = 0.001). In both time periods, the most frequent rating is 3. However, the mean rating of general health before therapy is 2.6 and after therapy is 3.2. Since improvement in health and quality of life was observed in almost all treatment groups, this indicates that radioactive iodine therapy is suitable for all age groups. The quality of health of the target group of subjects before and after thyroid therapy with radioactive iodine I-131 increased significantly after therapy.
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